Rules of Nomenclature
  

Key to nomenclaturea used for tryptophan biosynthetic pathway

New gene name
Prior gene name
Protein domain encoded

trpAa
trpE
Anthranilate synthase: aminase subunit (α)
trpAb
trpG
Anthranilate synthase: amidotransferase subunit (β)
trpB
trpD
Anthranilate phosphoribosyl transferase
trpC
trpF
Phosphoribosyl-anthranilate isomerase
trpD
trpC
Indoleglycerol phosphate synthase
trpEa
trpA
Tryptophan synthase, α subunit
trpEb
trpB
Tryptophan synthase, β subunit

a The nomenclature is at the level of catalytic domain in the order of reaction steps in the pathway. See [Ref] for a detailed rationale supporting the new nomenclature. Overall reactions of tight complexes are assigned one capital letter, with α and β subunits assigned the corresponding lowercase 'a' and 'b' respectively. The convention of a bullet denotes a fusion, for example, trpDtrpC.



L O S   A L A M O S   N A T I O N A L   L A B O R A T O R Y • Est 1943
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